AEROSOLIZED PLUS INTRAVENOUS COLISTIN VS INTRAVENOUS COLISTIN ALONE FOR THE TREATMENT OF NOSOCOMIAL PNEUMONIA DUE TO MULTIDRUG-RESISTANT GRAM-NEGATIVE BACTERIA: A RETROSPECTIVE COHORT STUDY

Aerosolized plus intravenous colistin vs intravenous colistin alone for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria: A retrospective cohort study

Objective: To compare the effectiveness and safety of aerosolized (AER) plus intravenous (IV) colistin with IV colistin alone in patients with nosocomial pneumonia (NP) due to multidrug-resistant (MDR) Gram-negative bacteria.Methods: This was a retrospective cohort study of adults with NP who received IV colistin alone or in combination with AER co

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Influence of Type and Neutralisation Capacity of Antacids on Dissolution Rate of Ciprofloxacin and Moxifloxacin from Tablets

Dissolution rate of two fluoroquinolone antibiotics (ciprofloxacin and moxifloxacin) was analysed in presence/absence of three antacid formulations.Disintegration time and neutralisation capacity of antacid tablets were also checked.Variation in disintegration time LEAVE-IN MOUSSE indicated the importance of this parameter, and allowed evaluation o

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